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Rezultatele cercetării OncoGen publicate în reviste internaționale de top

2025

1. Popoiu T-A, Cimpean AM, Bojin F, Cerbu S, Gug M-C, Pirvu C-A, Pantea S, Neagu A. Microengineered Breast Cancer Models: Shaping the Future of Personalized Oncology. Cancers, 2025; 17: 3160

2. Goje ID, Goje GI, Ordodi VL, Ciobotaru VG, Ivan VS, Buzaș R, Tunea O, Bojin F, Lighezan DF. Doxorubicin-Induced Cardiotoxicity and the Emerging Role of SGLT2 Inhibitors: From Glycemic Control to Cardio-Oncology. Pharmaceuticals, 2025; 18: 681

3. Vîlcu A, Comarița IK, Constantin A, Alexandru N, Nemecz M, Safciuc F, Bojin F, Paunescu V, Georgescu A. Innovative Therapy with Stem Cell-Derived Extracellular Vesicles on Cardiac Hypertrophy in an Animal Model of Atherosclerosis; Elucidation of the Molecular Mechanisms Involved in the Repair Process. Biomolecules, 2025; 15(10)

4. Pricop MA, Negrea A, Ciopec M, Pascu IB, Oprean C, Lukinich-Gruia AT, Cristea IM, Ivan A, Paunescu V, Tatu CA. Aristolochic Acid I Adsorption onto Activated Carbon: Kinetics, Equilibrium, and Thermodynamic Studies. Processes, 2025; 13(11)

5. Ivan A, Pricop MA, Lukinich-Gruia AT, Cristea IM, Negrea A, Pascu IB, Calma CL, Paunescu A, Paunescu V, Tatu CA. Cellular Metabolic Responses to Copper Nanoparticles: Comparison Between Normal and Breast Cancer Cells. International Journal of Molecular Sciences, 2025; 26(21)

6. Zimbru RI, Grijincu M, Tănasie G, Zimbru EL, Bojin MF, Buzan MR, Tamas TP, Cotarcă MD, Harich OO, Pătrașcu R, Haidar L, Ciurariu E, Marin KC, Păunescu V, Panaitescu C. Breaking Barriers: The Detrimental Effects of Combined Ragweed and House Dust Mite Allergen Extract Exposure on the Bronchial Epithelium. Applied Sciences, 2025; 15: 4113

7. Tirziu A, Bojin MF, Gavriliuc OI, Buzan RM, Zbircea LE, Grijincu M, Paunescu V. Anti-Her2 CAR-NK92 Cells and Their Exosomes: Generation, Characterization, and selective Cytotoxicity against Her2-Positive tumor Cells. International Journal of Molecular Sciences, 2025; 26(15): 7648

8. Ivan A, Lukinich-Gruia AT, Cristea IM, Pricop MA, Calma CL, Paunescu A, Tatu CA, Galuscan A, Paunescu V. In Vitro Antioxidant Effects of Coenzyme Q10 on Cellular Metabolism in Aged Mesenchymal Stem Cells. Applied Sciences Basel, 2025; 15(5): 2783

9. Tirziu A, Gavriliuc O-I, Bojin M-F, Paunescu V. Exploring CAR-PBMCs: A novel strategy against EGFR-positive tumor cells. Biomedicines, 2025; 13: 264

2024

1. Zimbru EL, Zimbru RI, Ordodi VL, Bojin FM, Crisnic D, andor M, Mirica SN, Hutu I, Tanasie G, Haidar L, Nistor D, Velcean L, Paunescu V, Panaitescu C. Rosuvastatin attenuates vascular dysfunction induced by high-fructose diets and allergic asthma in rats. Nutrients, 2024; 16(23): 4104

2. Ivan A, Lukinich-Gruia AT, Cristea IM, Pricop MA, Calma CL, Simina AG, Tatu CA, Galuscan A, Paunescu V. Quercetin and Mesenchymal Stem Cell Metabolism: A Comparative Analysis of Young and Senescent States. Molecules, 2024; 29(23): 5755

3. Pricop MA, Lukinich-Gruia AT, Cristea IM, Paunescu V, Tatu CA. Aristolochia clematitis L. Ethanolic Extracts: In Vitro Evaluation of Antioxidant Activity and Cytotoxicity on Caco-2 Cell Line. Plants-Basel, 2024; 13(21): 2987

4. Pahontu E, Pirvu CED, Visan DC, Socea LI, Apostol TV, Oprean C, Paunescu V, Ungurianu A, Margina DM, Codita I, Dumitrescu S, Draganescu D, Lupascu G. Evaluation of Antimicrobial, Antitumor, Antioxidant Activities, and Molecular Docking Studies of Some Co(II), Cu(II), Mn(II), Ni(II), Pd(II), and Pt(II) Complexes With a Schiff Base Derived From 2-Chloro-5-(trifluoromethyl)aniline. Applied Organometallic Chemistry, 2024; Corpus ID: 273645866

5. Lukinich_Gruia AT, Calma CL, Szekely FAE, Cristea IM, Pricop MA, Simina AG, Ordodi VL, Pavlovic NM, Tatu CA, Paunescu V. Mitochondrial Dysfunction in Aristolochic Acid I-Induced Kidney Diseases: What We Know and What We Do Not Know. Applied Sciences-Basel, 2024; 14(17): 7961

6. Udrea IA, Lukinich-Gruia AT, Paul C, Pricop MA, Dan MR, Paunescu V, Baloi A, Tatu CA, Vaszilcsin N, Ordodi V. Experimental Device for the "Green" Synthesis of Unbranched Aliphatic Esters C4-C8 Using an Audio Frequency Electric Field. Processes, 2024; 12(9): 1891

7. Zimbru RI, Zimbru EL, Ordodi VL, Bojin FM, Crisnic D, Grijincu M, Mirica SN, Tanasie G, Georgescu M, Hutu I, Haidar L, Paunescu V, Panaitescu C. The Impact of High-Fructose Diet and Co-Sensitization to House Dust Mites and Ragweed Pollen on the Modulation of Airway Reactivity and Serum Biomarkers in Rats. International Journal of Molecular Sciences, 2024; 25(16): 8868

8. Grijincu M, Buzan MR, Zbircea LE, Paunescu V, Panaitescu C. Prenatal Factors in the Development of Allergic Diseases. International Journal of Molecular Sciences, 2024; 25(12): 6359

9. Grijincu M, Tanasie G, Zbircea LE, Buzan MR, Tamas TP, Cotarca MD, Hutu I, Babaev E, Stolz F, Dorofeeva Y, Valenta R, Paunescu V, Panaitescu C, Chen KW. Non-Specific Lipid Transfer Protein Amb a 6 Is a Source-Specific Important Allergenic Molecule in Ragweed Pollen. International Journal of Molecular Sciences, 2024; 25(12): 6513

10. Zbircea LE, Buzan MR, Grijincu M, Tamas TP, Vulpe CB, Hutu I, Paunescu V, Panaitescu C, Chen KW. Cross-Reactivity of Ragweed Pollen Calcium-Binding Proteins and IgE Sensitization in a Ragweed-Allergic Population from Western Romania. Advances in Respiratory Medicine, 2024; 92(3): 218-229

11. Zbircea LE, Buzan MR, Grijincu M, Cotarca MD, Tamas TP, Haidar L, Tanasie G, Hutu I, Babaev E, Stolz F, Valenta R, Paunescu V, Panaitescu C, Chen KW. Heterogenous Induction of Blocking Antibodies against Ragweed Allergen Molecules by Allergen Extract-Based Immunotherapy Vaccines. Vaccines, 2024; 12(6): 635

12. Buzan MR, Grijincu M, Zbircea LE, Haidar L, Tamas TP, Cotarca MD, Tanasie G, Weber M, Babaev E, Stolz F, Valenta R, Paunescu V, Panaitescu C, Chen KW. Insect Cell-Expressed Major Ragweed Allergen Amb a 1.01 Exhibits Similar Allergenic Properties to Its Natural Counterpart from Common Ragweed Pollen. International Journal of Molecular Sciences, 2024; 25(10): 5175

13. Arjoca S, Bojin F, Neagu M, Paunescu A, Neagu A, Paunescu V. Hydrogel extrusion speed measurement for the optimization of bioprinting parameters. Gels, 2024; 10(2): 103

2023

1. Ivan A, Cristea MI, telea A, Oprean C, Galuscan A, Tatu C, Paunescu V. Stem cells derived from exfoliated deciduous teeth functional assessment: Exploring the changes of free fatty acids composition during cultivation. International Journal of Molecular Sciences, 2023; 24(24): 17249

2. Habago SD, Ordodi V, Bojin F, Vesa SC, Moldovan V, Paunescu V, Ionescu D. Inhibitory effects of lidocaine on colon carcinoma progression in a rat model: a pilot study. Br J Anaesth. 2023; 131(5): E163-E165

3. Harich OO, Gavriliuc OI, Ordodi VL, Tirziu A, Paunescu V, Panaitescu C, Bojin MF. In Vitro Study of the Multimodal Effect of Na+/K+ ATPase Blocker Ouabain on the Tumor Microenvironment and Malignant Cells. Biomedicines, 2023; 11: 2205

4. Tirziu, A., Avram S., Mada L., Crisan-Vida M., Popovici C., Popovici D., Faur C., Duda-Seiman C., Paunescu V., Vernic, C. Design of a Synthetic Long Peptide Vaccine Targeting HPV-16 and-18 Using Immunoinformatic Methods. Pharmaceutics. 2023, 15, 7

5. Habago S.D., Ordodi V., Bojin F., Vesa S.C., Moldovan V., Paunescu V., Ionescu D. Inhibitory effects of lidocaine on colon carcinoma progression in a rat model: a pilot study. British Journal of Anesthesia, 2023, 131, 5: E163-E165

6. Zbîrcea L-E., Buzan M-R., Grijincu M., Babaev E., Stolz F., Valenta R., Păunescu V., Panaitescu C., Chen K-W. Relationship between IgE Levels Specific for Ragweed Pollen Extract, Amb a 1 and Cross-Reactive Allergen Molecules. International Journal of Molecular Sciences. 2023; 24(4):4040

7. Tamaș T.P., Buzan R.M., Zbîrcea L.E., Cotarcă M.D., Grijincu M., Păunescu V., Panaitescu C., Chen C.W. Ragweed Major Allergen Amb a 11 Recombinant Production and Clinical Implications. Biomolecules, 2023, 13(1), 182

2022

1. Lukinich-Gruia A.T., Nortier J., Pavlović N.M., Milovanović D., Popović M., Drăghia L.P., Păunescu V., Tatu C.A. Aristolochic acid I as an emerging biogenic contaminant involved in chronic kidney diseases: A comprehensive review. Chemosphere, 2022, Feb 26; 297:134111

2. Zabel M., Weber M., Kratzer B., et al., Panaitescu C.B., et al., Valenta R., Pickl W.F. Art v 1 IgE epitopes of patients and humanized mice are conformational. J Allergy Clin Immunol., 2022

3. Constantin A., Comarita I.K., Alexandru N., Filippi A., Bojin F., Gherghiceanu M., Vilcu A., Nemecx M., Niculescu L.S., Paunescu V., Georgescu A. Stem cell-derived extracellular vesicles reduce the expression of molecules involved in cardiac hypertrophy. Frontiers in Pharmacology, 2022; 13: 1003684

4. Tirziu A., Paunescu V. Cytotoxic T-Cell-Based Vaccine against SARS-CoV-2: A Hybrid Immunoinformatic Approach. Vaccines, 2022; 10(2): 218

5. Barbulescu G.I., Bojin F.M., Ordodi V.L., Goje I.D., Barbulescu A.S., Paunescu V. Decellularized Extracellular Matrix Scaffolds for Cardiovascular Tissue Engineering: Current Techniques and Challenges. International Journal of Molecular Sciences, 2022; 23(21): 13040

2021

1. Bojin F., Robu A., Bejenariu M.I., Ordodi V., Olteanu E., Cean A., Popescu R., Neagu M., Gavriliuc O., Neagu A., Arjoca S., Paunescu V. 3D Bioprinting of model tissue that mimic the tumor microenvironment. Micromachines, 2021; 12: 535

2. Wanlin Guo, Jiayin Zhang, Zhihan Sun, William H. Orem, Calin A. Tatu, Niko S. Radulović, Dragan Milovanović, Nikola M. Pavlović, Wan Chan Analysis of Polycyclic Aromatic Hydrocarbons and Phthalate Esters in Soil and Food Grains from the Balkan Peninsula. Environmental Science & Technology., 2021

2020

1. Matricardi P.M., Dramburg S., Alvarez-Perea A., ..., Panaitescu C., et al. The role of mobile health technologies in allergy care: An EAACI position paper. Allergy. 2020; 75(2): 259-272

2. Niespodziana K., Borochova K., Pazderova P., ..., Panaitescu C., et al. Toward personalization of asthma treatment according to trigger factors. J Allergy Clin Immunol. 2020; 145(6): 1529-1534

2019

1. Bousquet J., Hellings P.W., Agache I., the Mobile Airways Sentinel network M (Panaitescu C. et al). Allergic Rhinitis and its Impact on Asthma (ARIA) Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile technology. Journal of Allergy and Clinical Immunology. 2019; 143, 3: 864-879

2018

1. Chen Kuan-Wei, Marusciac L., Tamas P.T., Valenta R., Panaitescu (Bunu) C. Ragweed Pollen Allergy: Burden, Characteristics, and Management of an Imported Allergen Source in Europe. International archives of allergy and immunology, 2018, Vol.176(3-4), pp.163-180

2014

1. Paunescu V., Bojin F.M., Gavriliuc O.I., Taculescu E.A., Ianos R., Ordodi V.L., Iman V.F., Tatu C.A. Enucleation: a possible mechanism of cancer cell death. J Cell Mol Med, 2014; 18(6): 962-965

2011

1. Paunescu V., Bojin F.M., Tatu C.A., Gavriliuc O.I., Rosca A., Gruia A.T., Tanasie G., Bunu C., Crisnic D., Gherghiceanu M., Tatu F.R., Tatu C.S., Vermesan S. Tumour-associated fibroblasts and mesenchymal stem cells: more similarities than differences. J Cell Mol Med. 2011 Mar; 15(3): 635-46

2007

1. Paunescu V., Deak E., Herman D., Siska I.R., Tanasie G., Bunu C., Anghel S., Tatu C.A., Oprea T.I., Henschler R., Rüster B. In vitro differentiation of human mesenchymal stem cells to epithelial lineage. Journal of cellular and molecular medicine. 2007 May; 11(3): 502-8